ORIGINAL ARTICLE - Case Report
CITATION: Ekvtimishvili E, Meher A, Johnson J. Echoes of Trauma: DSA-Guided Coil Embolization for Carotid Cavernous Fistula Presenting with Ocular Bruit & Pulsatile Exophthalmos. Discoveries 2025, 13(1): e203. DOI: 10.15190/d.2025.2
Echoes of Trauma: DSA-Guided Coil Embolization for Carotid Cavernous Fistula Presenting with Ocular Bruit and Pulsatile Exophthalmos
Erekle Ekvtimishvili 1, Arpita Meher 2, *, Jessen Johnson 2
- 1 MD, PhD, Assistant Professor at TSMU, Head of Endovascular Neurosurgery Department, High Technology Medical Center, University Clinic, Tbilisi, Georgia
- 2 Department of Medicine, Tbilisi State Medical University, Tbilisi, Georgia
* Corresponding author: Arpita Meher, Department of Medicine, Tbilisi State Medical University, Tbilisi, Georgia; Email: meher.arpita65@gmail.com
Abstract
Carotid-Cavernous Fistulas (CCFs) are abnormal arteriovenous connections between the carotid artery and the cavernous sinus, resulting from trauma. This case report presents a 47-year-old male who developed a CCF following a road traffic accident. The patient exhibited symptoms such as pulsatile exophthalmos and an ocular bruit, characteristic of CCFs. Diagnosis was confirmed through Digital Subtraction Angiography (DSA), revealed the origin of the fistula. The patient was treated using a novel combined approach of microsurgery and endovascular intervention, involving ligation of the internal carotid artery and transarterial coil embolization. The treatment resulted in rapid resolution of symptoms, including the pulsatile exophthalmos and ocular bruit. This case highlights the importance of a multidisciplinary approach, blending microsurgical and advanced endovascular techniques, in effectively managing traumatic CCFs. The study underscores the value of early diagnosis and the evolving role of minimally invasive procedures in improving patient outcomes.
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REFERENCES
1. Henderson AD, Miller NR. Carotid-cavernous fistula: current concepts in aetiology, investigation, and management. Eye [Internet]. 2017 Nov 3 [cited 2019 Apr 24];32(2):164–72.
2. Sumdani H, Aguilar-Salinas P, Avila MJ, El-Ghanem M, Dumont TM. Carotid Cavernous Fistula Treatment via Flow Diversion: A Systematic Review of the Literature. World Neurosurgery [Internet]. 2021 May 1;149:e369–77.
3. Pavlos Texakalidis, Tzoumas A, Xenos D, Rivet DJ, Reavey-Cantwell J. Carotid cavernous fistula (CCF) treatment approaches: A systematic literature review and meta-analysis of transarterial and transvenous embolization for direct and indirect CCFs. Clinical Neurology and Neurosurgery. 2021 May 1;204:106601–1.
4. Sun P, Chai Y, Fang W, Chen H, Long Q, Zhao Z, et al. Case report: Spontaneous carotid-cavernous fistula associated with persistent primitive trigeminal artery aneurysm rupture. Frontiers in Neurology. 2022 Sep 6;13.
5. Jiang H, Zeng Q, Jiang W. Carotid-cavernous sinus fistula with primary clinical manifestation of cerebral infarction: description of two cases. Quantitative Imaging in Medicine and Surgery [Internet]. 2023 Feb 23 [cited 2025 Mar 30];13(3):2021–5.
6. Hooman Hamedani, Hellmann D, Boyce W, Alesio ND. Traumatic carotid-cavernous fistula: A case report. Radiology Case Reports. 2022 Apr 7;17(6):1955–8.
7. Neeharika Krothapalli, Fayad M, Sussman E, Bruno C, Ollenschleger M, Mehta T. Carotid cavernous fistula. Brain Circulation [Internet]. 2023 Jan 1 [cited 2025 Mar 6];9(1):30–4.
8. Al-Boqami BA, Tammar RS, Alharbi SE, Ahmed ZM, Alharbi A. Endovascular Intervention for a Carotid-Cavernous Fistula: A Case Report. Cureus. 2023 Sep 8.
9. Sharma R, Ponder C, Kamran M, Chacko J, Kapoor N, Mylavarapu K, et al. Bilateral Carotid-Cavernous Fistula: A Diagnostic and Therapeutic Challenge. Journal of investigative medicine high impact case reports [Internet]. 2022 Jan 1 [cited 2024 May 24];10:232470962210941-232470962210941.