2014, Volume 2 - Issue 4

INTERVIEW Article


Discoveries Interview: Professor George A. Calin on non-coding RNAs

Read FULL ARTICLE (pdf)  Abstract, Citation & References  DOI: 10.15190/d.2014.24 

Professor George A. Calin, MD, PhD, is a Professor in Experimental Therapeutics, Division of Cancer Medicine, and Co-Director of the Center for RNA Interference and Non-Coding RNAs, at MD Anderson Cancer Center, Houston, TX, USA.

Professor George Calin received his MD and PhD degrees from “Carol Davila” University of Medicine and Pharmacy, in Bucharest, Romania. Prof. Calin continued his cancer genomics training in Massimo Negrini’s laboratory at University of Ferrara, in Italy. In 2000 he became a postdoctoral fellow at Kimmel Cancer Center in Philadelphia, PA, in Carlo Croce’s laboratory. Before joining the MD Anderson Cancer Center, he held research and teaching positions at Thomas Jefferson University, in Philadelphia and Ohio State University, in Columbus. Read more 

ORIGINAL Articles


Thrombospondin-1 Modulates Actin Filament Remodeling and Cell Motility in Mouse Mammary Tumor cells in Vitro

Dorothy Ndishabandi, Cameron Duquette, Ghita El-Moatassim Billah, Millys Reyes, Mark Duquette, Jack Lawler, Shideh Kazerounian*
Read FULL ARTICLE (pdf)  Abstract, Citation & References  DOI: 10.15190/d.2014.23 
Corresp. author's affiliation: * Department of Pediatrics, Division of Genetics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.


The role of mutations at codons 32, 47, 54, and 90 in HIV-1 protease flap dynamics

Poorvi Chordia, Tamaria G. Dewdney, Bradley Keusch, Benjamin D. Kuiper, Kyla Ross, Iulia A. Kovari, Rodger  MacArthur, Hossein Salimnia, Ladislau C. Kovari*
Read FULL ARTICLE (pdf)  Abstract, Citation & References  DOI: 10.15190/d.2014.19
Corresp. author's affiliation: * Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit, MI, USA.

PERSPECTIVE Articles


Key principles of miRNA involvement in human diseases

Dana Elena Giza, Catalin Vasilescu, George A. Calin*
Read FULL ARTICLE (pdf)  Abstract, Citation & References  DOI: 10.15190/d.2014.26 
Corresp. author's affiliation: * Co-Director of the Center for RNA Interference and Non-Coding RNAs, Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, TX, USA.


New perspective in heart failure management: could myosin activators be the answer?

Stefan Andrei*, Corina Iorgoveanu
Read FULL ARTICLE (pdf)  Abstract, Citation & References  DOI: 10.15190/d.2014.25  
Corresp. author's affiliation: * CNHO des Quinze-Vingts, Service de Médecine Interne, Paris, France